Adhesion G Protein-Coupled Receptor F1 (ADGRF1) Antibody

Background

ADGRF1, also known as GPR110, is a member of the adhesion G-protein coupled receptor (GPCR) family. This receptor is characterized by its large extracellular domain, which facilitates cell-cell and cell-matrix interactions. ADGRF1 is expressed in various tissues, including the brain, lungs, and immune cells, suggesting diverse physiological roles. It has been implicated in neural development, immune regulation, and possibly cancer progression. The receptor’s activation and downstream signaling mechanisms are still under investigation, but its role in modulating cellular adhesion and signaling pathways highlights its potential therapeutic relevance in oncology and immunology.