Adhesion G Protein-Coupled Receptor E2 (ADGRE2) Antibody
169€ (20 µg)
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935106861
info@markelab.com
name
Adhesion G Protein-Coupled Receptor E2 (ADGRE2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx349435
tested applications
ELISA, IHC, IF/ICC
Description
Adhesion G Protein-Coupled Receptor E2 (ADGRE2) Antibody is a Rabbit Polyclonal antibody for the detection of Human ADGRE2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Adhesion G Protein-Coupled Receptor E2 (ADGRE2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G chromatography. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9UHX3 |
| Gene ID | 30817 |
| Alias | ADGRE2,EMR2,EGF-like module-containing mucin-like hormone receptor-like 2,CD312 |
| Background | Antibody anti-ADGRE2 |
| Status | RUO |
Descripción
ADGRE2, or EMR2, is an adhesion GPCR expressed on myeloid cells, including monocytes, macrophages, and eosinophils, where it modulates immune responses and cellular adhesion. Its structure includes multiple extracellular EGF-like domains that enable interactions with ligands and the extracellular matrix. ADGRE2 is involved in processes such as cell migration, adhesion, and activation during inflammatory and immune responses. Mutations in ADGRE2 have been linked to vibratory urticaria, a rare inherited disorder characterized by hives triggered by mechanical vibrations, suggesting its role in mechanosensation and immune cell activation. The receptor’s involvement in eosinophil-mediated responses also points to potential roles in allergic diseases and eosinophilic inflammation.
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