Adenylate Kinase 4, Mitochondrial (AK3L1) Antibody
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935106861
info@markelab.com
Precio
364€ (100 µg)
Antibody anti-AK4
proveedor
Abbexareference
abx230247Tested Applications
ELISA, WB, IHCreactivity
Human, Mouse, Ratstatus
RUOclonality
PolyclonalDescripción
AK3L1 Antibody is a Rabbit Polyclonal against AK3L1.
Background
AK4, also localized in the mitochondrial matrix, is a catalytically inactive adenylate kinase homolog involved in stress response and ATP metabolism regulation. Despite lacking enzymatic activity, AK4 interacts with other AK isoforms to regulate energy homeostasis under stress conditions, including hypoxia or metabolic reprogramming. AK4 expression is elevated in some cancers, suggesting a role in tumor progression and survival. It functions in modulating mitochondrial dynamics and improving resistance to oxidative stress, particularly in high-metabolic tissues like the heart. AK4 has also been linked to cellular signaling pathways regulating apoptosis, energy metabolism, and DNA repair.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human, Mouse, Rat
immunogen target
Adenylate Kinase 4, Mitochondrial (AK3L1)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB, IHC
purity
≥ 95% (SDS-PAGE)
purification
Purified by immunogen affinity chromatography.
recommended dilution
WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
size 1
100 µg
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
AK4
dry ice
No
availability
Shipped within 5-12 working days.
alias
AK4,AK3,AK3L1,AK3L2
uniprot id
note
Concentration: 2 mg/ml - Validity: 12 months.
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