Pituitary Adenylate Cyclase-Activating Polypeptide Type I Receptor (ADCYAP1R1) Antibody

Name: Pituitary Adenylate Cyclase-Activating Polypeptide Type I Receptor (ADCYAP1R1) Antibody
Brand: Abbexa
SKU: abx037204
Price: 357.5 EUR
Availability: OnlineOnly

Pida mas información

935106861

info@markelab.com

Precio

357.5€ (100 µg)

Antibody anti-ADCYAP1R1

proveedor

Abbexa

reference

abx037204

Tested Applications

ELISA, WB

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

Rabbit Polyclonal against the ADCYAP1R1 protein.

Background

The ADCYAP1R1 gene encodes the PAC1 receptor, which belongs to the class B G-protein-coupled receptor (GPCR) family. This receptor is the primary target of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP), a neuropeptide that regulates various physiological processes. ADCYAP1R1 is widely expressed in the central nervous system (CNS), endocrine glands, and peripheral tissues. Upon PACAP binding, it activates adenylyl cyclase and stimulates the production of cyclic AMP (cAMP), leading to downstream signal transduction. ADCYAP1R1 plays critical roles in neuroprotection, stress response, metabolism, and immune regulation. Dysregulation of this receptor has been linked to neurological disorders, anxiety, depression, and inflammatory diseases, underscoring its importance in maintaining physiological homeostasis.

Características del producto

clonality

Polyclonal

reactivity

Human

immunogen target

Pituitary Adenylate Cyclase-Activating Polypeptide Type I Receptor (ADCYAP1R1)

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

Lyophilized

tested applications

ELISA, WB

purification

Purified by antigen affinity column chromatography.

recommended dilution

ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.

buffer

Prior to lyophilization: 1% BSA and 0.02% NaN3.

size 1

100 µg

size 2

1 mg

storage

Store at -20 °C. Avoid repeated freeze/thaw cycles.

or code

ADCYAP1R1

dry ice

availability

Shipped within 7-15 working days.

alias

ADCYAP1R1,PAC1R,PVR1,PACAP receptor 1,PACAP type IA receptor,PACAPR1,pituitary adenylate cyclase activating polypeptide 1 receptor,PACAP1-R,adenylate cyclase activating polypeptide 1 receptor 1,adenylate cyclase activating polypeptide 1 receptor type 1,ADCYAP receptor type 1,PAC1,PACAPR, PACAPRI

uniprot id

https://www.uniprot.org/uniprotkb/P41586

gene id

https://www.ncbi.nlm.nih.gov/gene/117

note

Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. -

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Human ADCYAP1R1(Pituitary adenylate cyclase-activating polypeptide type I receptor) ELISA Kit

proveedor

FineTest

reference

EH1765

reactivity

human

status

RUO

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