Pituitary Adenylate Cyclase-Activating Polypeptide Type I Receptor (ADCYAP1R1) Antibody
195€ (20 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Pituitary Adenylate Cyclase-Activating Polypeptide Type I Receptor (ADCYAP1R1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx002241
tested applications
ELISA, WB, IF/ICC
Description
ADCYAP1R1 Antibody is a Rabbit Polyclonal antibody against ADCYAP1R1. This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Pituitary Adenylate Cyclase-Activating Polypeptide Type I Receptor (ADCYAP1R1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IF/ICC |
| Buffer | PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P41586 |
| Gene ID | 117 |
| NCBI Accession | NP_001109.2 |
| OMIM | 102981 |
| Alias | ADCYAP1R1,PAC1R,PVR1,PACAP receptor 1,PACAP type IA receptor,PACAPR1,pituitary adenylate cyclase activating polypeptide 1 receptor,PACAP1-R,adenylate cyclase activating polypeptide 1 receptor 1,adenylate cyclase activating polypeptide 1 receptor type 1,ADCYAP receptor type 1,PAC1,PACAPR, PACAPRI |
| Background | Antibody anti-ADCYAP1R1 |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
The ADCYAP1R1 gene encodes the PAC1 receptor, which belongs to the class B G-protein-coupled receptor (GPCR) family. This receptor is the primary target of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP), a neuropeptide that regulates various physiological processes. ADCYAP1R1 is widely expressed in the central nervous system (CNS), endocrine glands, and peripheral tissues. Upon PACAP binding, it activates adenylyl cyclase and stimulates the production of cyclic AMP (cAMP), leading to downstream signal transduction. ADCYAP1R1 plays critical roles in neuroprotection, stress response, metabolism, and immune regulation. Dysregulation of this receptor has been linked to neurological disorders, anxiety, depression, and inflammatory diseases, underscoring its importance in maintaining physiological homeostasis.
Related Products
Human ADCYAP1R1(Pituitary adenylate cyclase-activating polypeptide type I receptor) ELISA Kit
Ver Producto
Pituitary Adenylate Cyclase-Activating Polypeptide Type I Receptor (ADCYAP1R1) Antibody
ADCYAP1R1 Antibody is a Rabbit Polyclonal antibody against ADCYAP1R1. This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified.
Ver Producto
Pituitary Adenylate Cyclase-Activating Polypeptide Type I Receptor (ADCYAP1R1) Antibody
Rabbit Polyclonal against the ADCYAP1R1 protein.
Ver Producto