Adenylate Cyclase 5 (ADCY5) Antibody
260€ (50 µl)
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Name
Adenylate Cyclase 5 (ADCY5) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx214922
Tested Applications
ELISA, IHC
Description
ADCY5 Antibody is a Rabbit Polyclonal against ADCY5.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Adenylate Cyclase 5 (ADCY5) Immunogen: Synthetic peptide of human ADCY5. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1/2000 - 1/10000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O95622 |
| Gene ID | 111 |
| Alias | AC5, DSKOD, FDFM |
| Background | Antibody anti-ADCY5 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ADCY5 is a G-protein-regulated, membrane-bound enzyme highly expressed in the heart and brain. It is critical for cardiac function, including regulating heart rate and contractility through cAMP production. In the brain, ADCY5 mediates dopamine signaling and contributes to motor control. Mutations in ADCY5 have been linked to familial dyskinesia and neurological movement disorders. It is also implicated in cardiac pathologies, such as heart failure, due to its central role in cAMP-dependent signaling in cardiomyocytes.
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