Adenylate Cyclase 5 (ADCY5) Antibody

Este producto es parte de ADCY - Adenylate Cyclase Type
Product Graph
780€ (1 ml)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Adenylate Cyclase 5 (ADCY5) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx171087
tested applications
WB, IHC, IF/ICC

Description

This product is currently in development. The lead time for this product may be several months. Please contact us at

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetAdenylate Cyclase 5 (ADCY5)
HostMouse
ReactivityHuman
Recommended DilutionWB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
ClonalityMonoclonal
ConjugationUnconjugated
PurificationPurified by Protein A and Protein G affinity chromatography.
Size 11 ml
FormLiquid
Tested ApplicationsWB, IHC, IF/ICC
Buffer0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
AvailabilityPlease enquire.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
AliasAC5, DSKOD, FDFM
BackgroundAntibody anti-ADCY5
StatusRUO

Descripción

ADCY5 is a G-protein-regulated, membrane-bound enzyme highly expressed in the heart and brain. It is critical for cardiac function, including regulating heart rate and contractility through cAMP production. In the brain, ADCY5 mediates dopamine signaling and contributes to motor control. Mutations in ADCY5 have been linked to familial dyskinesia and neurological movement disorders. It is also implicated in cardiac pathologies, such as heart failure, due to its central role in cAMP-dependent signaling in cardiomyocytes.

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