Adenylate Cyclase 4 (ADCY4) Antibody
221€ (50 µg)
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Name
Adenylate Cyclase 4 (ADCY4) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx327502
Tested Applications
ELISA, WB
Description
ADCY4 Antibody is a Rabbit Polyclonal against ADCY4.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Adenylate Cyclase 4 (ADCY4) Immunogen: Synthesized peptide derived from the Internal region of human A Cyclase IV. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1/20000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8NFM4 |
| Gene ID | 196883 |
| Alias | AC4 |
| Background | Antibody anti-ADCY4 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ADCY4 is expressed in various tissues, including the brain, heart, and lungs. As a member of the adenylate cyclase family, it catalyzes the conversion of ATP to cAMP, an important signaling molecule in cellular responses. ADCY4 is activated by G-proteins and forskolin but is not sensitive to calcium/calmodulin regulation. It plays critical roles in signal transduction pathways involved in neurotransmission, immune response, and cardiovascular functions. Studies suggest that alterations in ADCY4 activity may contribute to inflammatory processes and neurological dysfunction.
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