Adenylate Cyclase 4 (ADCY4) Antibody
169€ (20 µl)
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935106861
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name
Adenylate Cyclase 4 (ADCY4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx321174
tested applications
ELISA, IHC
Description
ADCY4 Antibody is a Rabbit Polyclonal against ADCY4.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Adenylate Cyclase 4 (ADCY4) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 20 µl |
| Size 2 | 50 µl |
| Size 3 | 100 µl |
| Size 4 | 200 µl |
| Size 5 | 1 ml |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8NFM4 |
| Gene ID | 196883 |
| NCBI Accession | NP_001185497.1, NM_001198568.1 |
| OMIM | 600292 |
| Alias | AC4 |
| Background | Antibody anti-ADCY4 |
| Status | RUO |
Descripción
ADCY4 is expressed in various tissues, including the brain, heart, and lungs. As a member of the adenylate cyclase family, it catalyzes the conversion of ATP to cAMP, an important signaling molecule in cellular responses. ADCY4 is activated by G-proteins and forskolin but is not sensitive to calcium/calmodulin regulation. It plays critical roles in signal transduction pathways involved in neurotransmission, immune response, and cardiovascular functions. Studies suggest that alterations in ADCY4 activity may contribute to inflammatory processes and neurological dysfunction.
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