Adenylate Cyclase 2, Brain (ADCY2) Antibody
351€ (100 µg)
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Name
Adenylate Cyclase 2, Brain (ADCY2) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx375821
Tested Applications
ELISA, WB
Description
Adenylate Cyclase 2, Brain (ADCY2) Antibody is a Rabbit Polyclonal antibody against Adenylate Cyclase 2, Brain (ADCY2).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Adenylate Cyclase 2, Brain (ADCY2) Immunogen: Synthesized peptide derived from Human Adenylate Cyclase 2, Brain (490-570 AA) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q08462 |
| Gene ID | 108 |
| Alias | AC2,HBAC2,ATP pyrophosphate-lyase 2 |
| Background | Antibody anti-ADCY2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ADCY2 is a transmembrane enzyme expressed widely in the central nervous system and cardiac tissues. It is activated by Gαs proteins and regulated by forskolin and calcium signaling. ADCY2 plays a central role in converting ATP to cAMP, which mediates various cellular responses, including neurotransmission, hormone signaling, and metabolism. It is particularly important in modulating synaptic communication and neuronal excitability. Mutations or alterations in ADCY2 expression have been associated with mood disorders, including schizophrenia and bipolar disorder, highlighting its significance in brain function.
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