ADCY5 / ADCY6 Antibody
221€ (50 µg)
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Name
ADCY5 / ADCY6 Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx329221
Tested Applications
ELISA, WB, IHC, IF/ICC
Description
ADCY5/ADCY6 Antibody is a Rabbit Polyclonal against ADCY5/ADCY6.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: ADCY5/ADCY6 Immunogen: Synthesized peptide derived from the C-terminal region of human A Cyclase V/VI. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/300, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O95622, O43306 |
| Alias | AC5, DSKOD, FDFM |
| Background | Antibody anti-ADCY5 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ADCY5 is a G-protein-regulated, membrane-bound enzyme highly expressed in the heart and brain. It is critical for cardiac function, including regulating heart rate and contractility through cAMP production. In the brain, ADCY5 mediates dopamine signaling and contributes to motor control. Mutations in ADCY5 have been linked to familial dyskinesia and neurological movement disorders. It is also implicated in cardiac pathologies, such as heart failure, due to its central role in cAMP-dependent signaling in cardiomyocytes.
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