ADAMTS-Like Protein 4 (ADAMTSL4) Antibody

Name: ADAMTS-Like Protein 4 (ADAMTSL4) Antibody
Brand: Abbexa
SKU: abx321173
Price: 169 EUR
Availability: OnlineOnly

Este producto es parte de ADAMTSL - ADAMTS-like protein

Pida mas información

935106861

info@markelab.com

Precio

169€ (20 µl)

Antibody anti-ADAMTSL4

proveedor

Abbexa

reference

abx321173

Tested Applications

ELISA, IHC

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

ADAMTSL4 Antibody is a Rabbit Polyclonal against ADAMTSL4.

Background

ADAMTSL4 is a non-enzymatic member of the ADAMTS-like protein family, characterized by TSRs and cysteine-rich domains. It plays a significant role in fibrillin microfibril organization and contributes to the structural integrity of the ECM. Mutations in the ADAMTSL4 gene are associated with ectopia lentis, a disorder involving lens dislocation in the eye, and other connective tissue abnormalities. ADAMTSL4 does not exhibit catalytic activity but regulates fibrillin microfibril assembly and modulates TGF-β signaling. It is widely expressed in ocular tissues, connective tissues, and the cardiovascular system, underscoring its role in ECM organization and developmental processes.

Características del producto

clonality

Polyclonal

reactivity

Human

immunogen target

ADAMTS-Like Protein 4 (ADAMTSL4)

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, IHC

purification

Antigen Affinity Chromatography.

recommended dilution

IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.

buffer

PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol.

size 1

20 µl

size 2

50 µl

size 3

100 µl

size 4

200 µl

size 5

1 ml

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

ADAMTSL4

dry ice

availability

Shipped within 5-10 working days.

alias

Thrombospondin repeat-containing protein 1,ADAMTSL-4

uniprot id

https://www.uniprot.org/uniprotkb/Q6UY14

gene id

https://www.ncbi.nlm.nih.gov/gene/54507

NCBI accession

NP_001275536.1, NM_001288607.1, NP_001275537.1, NM_001288608.1

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anti- ADAMTSL4 antibody

proveedor

FineTest

reference

FNab00147

Tested Applications

ELISA, WB, IHC, IP

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

Positive regulation of apoptosis. May facilitate FBN1 microfibril biogenesis.

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