ADAM Metallopeptidase With Thrombospondin Type 1 Motif 6 (ADAMTS6) Antibody

Este producto es parte de ADAMTS6 - ADAM metallopeptidase with thrombospondin type 1 motif 6
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260€ (50 µl)

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935106861
info@markelab.com
name
ADAM Metallopeptidase With Thrombospondin Type 1 Motif 6 (ADAMTS6) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx339725
tested applications
ELISA, IHC

Description

ADAMTS6 Antibody is a Rabbit Polyclonal against ADAMTS6.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
ADAM Metallopeptidase With Thrombospondin Type 1 Motif 6 (ADAMTS6)
Host
Rabbit
Reactivity
Human
Recommended Dilution
ELISA: 1/1000 - 1/5000, IHC: 1/15 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Antigen Affinity Chromatography.
Size 1
50 µl
Size 2
100 µl
Form
Liquid
Tested Applications
ELISA, IHC
Buffer
PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9UKP5
Gene ID
11174
Alias
A Disintegrin And Metalloproteinase With Thrombospondin Motifs 6,ADAM-TS 6,ADAMTS-6
Background
Antibody anti-ADAMTS6
Status
RUO

Descripción

ADAMTS6 ,A Disintegrin And Metalloproteinase with Thrombospondin Motifs 6 is a member of the ADAMTS (ADAM with thrombospondin motifs) family of proteases. ADAMTS6 belongs to a group of multidomain proteases characterized by the presence of a metalloproteinase domain, a disintegrin-like domain, and various thrombospondin type-1 (TSP-1) motifs. ADAMTS6 is expressed in various tissues, including skeletal muscle, heart, brain, kidney, and lung. Its expression pattern suggests potential roles in tissue development and homeostasis.ADAMTS6 has been implicated in several physiological and pathological processes. Studies suggest its involvement in ECM remodeling, particularly in the degradation and processing of proteoglycans and other ECM components. It may also play roles in angiogenesis, wound healing, and inflammation.Dysregulation of ADAMTS6 has been implicated in various diseases. For example, altered expression of ADAMTS6 has been reported in cancers, such as breast cancer, where it may influence tumor progression and metastasis. Additionally, mutations in the ADAMTS6 gene have been linked to certain genetic disorders and developmental abnormalities.

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