Acyl-CoA Synthetase Family Member 2 (ACSF2) Antibody
364€ (100 µg)
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935106861
info@markelab.com
name
Acyl-CoA Synthetase Family Member 2 (ACSF2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx230105
tested applications
ELISA, WB, IHC
Description
ACSF2 Antibody is a Rabbit Polyclonal against ACSF2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Acyl-CoA Synthetase Family Member 2 (ACSF2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/200 - 1/2000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96CM8 |
| Gene ID | 80221 |
| OMIM | 610465 |
| Alias | ACSMW,AVYV493 |
| Background | Antibody anti-ACSF2 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
ACSF2 is an acyl-CoA synthetase that plays a pivotal role in the activation of medium-chain fatty acids by converting them into their corresponding acyl-CoA derivatives, facilitating their incorporation into metabolic pathways such as β-oxidation, lipid biosynthesis, and signaling processes. It is predominantly expressed in metabolically active tissues such as the liver and kidney, where it helps maintain energy balance and lipid homeostasis during varying metabolic states. ACSF2 contributes to the formation of bioactive lipids and provides substrates for ATP production, making it integral to intermediary metabolism. Dysregulation of ACSF2 activity has been linked to metabolic disorders, including obesity and fatty acid oxidation deficiencies, where disrupted activation of fatty acids impairs energy production and lipid processing. Its enzymatic specificity underscores its critical role in maintaining cellular metabolic adaptability and systemic lipid regulation.
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