Acyl-CoA Synthetase Bubblegum Family Member 1 (ACSBG1) Antibody

Background

ACSBG1 is an enzyme that activates long-chain fatty acids by catalyzing their conversion into acyl-CoA esters, a critical step for their utilization in metabolic pathways, including β-oxidation, lipid biosynthesis, and signaling. It is predominantly expressed in tissues such as the brain and adrenal glands, where it supports processes requiring specialized lipid metabolism. ACSBG1 plays a significant role in maintaining lipid homeostasis and contributing to the production of myelin and steroid hormones by supplying activated fatty acids for biosynthetic processes. Dysregulation of ACSBG1 has been linked to neurological disorders and metabolic imbalances, highlighting its importance in brain lipid metabolism and systemic energy regulation. Its activity is essential for the management of cellular fatty acid pools and for adapting to changes in metabolic demands.