Family main features
Acyl-CoA Synthetase Bubblegum (ACSBG) family enzymes are a subset of acyl-CoA synthetases, which play crucial roles in lipid metabolism. These enzymes are responsible for catalyzing the activation of long-chain fatty acids by converting them into acyl-CoA, a key step in fatty acid metabolism. The name "Bubblegum" originates from a specific gene mutation identified in a Drosophila melanogaster mutant with a bubblegum-like phenotype.ACSBG1 play a central role in brain very long-chain fatty acids metabolism and myelinogenesis. ACSBG2 Can activate diverse saturated, monosaturated and polyunsaturated fatty acids. Has increased ability to activate oleic and linoleic acid. May play a role in spermatogenesis.
The structure of ACSBG family enzymes includes several characteristic features:
The ACSBG family is classified based on their substrate specificity and tissue distribution. Key members include:
ACSBG enzymes serve critical roles in various metabolic processes:
ACSBG enzymes interact with various molecules and pathways:
Dysfunction or mutations in ACSBG enzymes can lead to various metabolic disorders:
The Acyl-CoA Synthetase Bubblegum (ACSBG) family includes enzymes essential for the activation of long-chain fatty acids, converting them into acyl-CoA derivatives. This activation is critical for fatty acid metabolism, including β-oxidation and lipid biosynthesis. The ACSBG family comprises key members such as ACSBG1 and ACSBG2, each with specific functions and tissue distributions. Dysfunctions or mutations in these enzymes can lead to metabolic disorders, making them important targets for understanding and potentially treating diseases related to lipid metabolism. Understanding the structure, function, interactions, and clinical implications of ACSBG enzymes provides valuable insights into their roles in health and disease.
Acyl-CoA Synthetase Bubblegum Family Member 1(ACSBG1)
BG,BG1,BGM,GR-LACS,LPD
Acyl-CoA synthetase Bubblegum family member 2(ACSBG2)
BGR,BRGL,PRTD-NY3,PRTDNY3
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Primary Antibodies, ELISA Kits) relacionados con ACSBG-Acyl-CoA Synthetase Bubblegum Family
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 15 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | ACSBG2 | abx500632 | Human Long-chain-fatty-acid--CoA ligase ACSBG2 (ACSBG2) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q5FVE4 | RUO | ||
Abbexa | ACSBG1 | abx500629 | Mouse Long-chain-fatty-acid--CoA ligase ACSBG1 (ACSBG1) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q99PU5 | RUO | ||
Abbexa | ACSBG2 | abx500633 | Mouse Long-chain-fatty-acid--CoA ligase ACSBG2 (ACSBG2) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q2XU92 | RUO | ||
Abbexa | ACSBG1 | abx500630 | Rat Acyl-CoA Synthetase Bubblegum Family Member 1 (ACSBG1) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q924N5 | RUO | ||
Abbexa | ACSBG2 | abx500634 | Rat Acyl-CoA Synthetase Bubblegum Family Member 2 (ACSBG2) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | A1L1K7 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | ACSBG1 | abx301617 | Acyl-CoA Synthetase Bubblegum Family Member 1 (ACSBG1) Antibody | Human | Polyclonal | Rabbit | Acyl-CoA Synthetase Bubblegum Family Member 1 (ACSBG1) | Unconjugated | ELISA, IHC | 162.5 | 20 µg | Q96GR2 | RUO | |
Abbexa | ACSBG1 | abx310231 | Acyl-CoA Synthetase Bubblegum Family Member 1 (ACSBG1) Antibody (FITC) | Human | Polyclonal | Rabbit | Acyl-CoA Synthetase Bubblegum Family Member 1 (ACSBG1) | FITC | 162.5 | 20 µg | Q96GR2 | RUO | ||
Abbexa | ACSBG1 | abx310230 | Acyl-CoA Synthetase Bubblegum Family Member 1 (ACSBG1) Antibody (HRP) | Human | Polyclonal | Rabbit | Acyl-CoA Synthetase Bubblegum Family Member 1 (ACSBG1) | HRP | ELISA | 162.5 | 20 µg | Q96GR2 | RUO | |
Abbexa | ACSBG1 | abx310232 | Acyl-CoA Synthetase Bubblegum Family Member 1 (ACSBG1) Antibody (Biotin) | Human | Polyclonal | Rabbit | Acyl-CoA Synthetase Bubblegum Family Member 1 (ACSBG1) | Biotin | ELISA | 162.5 | 20 µg | Q96GR2 | RUO | |
Abbexa | ACSBG1 | abx241470 | Acyl-CoA Synthetase Bubblegum Family Member 1 (ACSBG1) Antibody | Human | Polyclonal | Rabbit | Acyl-CoA Synthetase Bubblegum Family Member 1 (ACSBG1) | Unconjugated | ELISA, IHC | 250 | 50 µl | Q96GR2 | RUO | |
Abbexa | ACSBG1 | abx241173 | Acyl-CoA Synthetase Bubblegum Family Member 1 (ACSBG1) Antibody | Human | Polyclonal | Rabbit | Acyl-CoA Synthetase Bubblegum Family Member 1 (ACSBG1) | Unconjugated | ELISA, IHC | 250 | 50 µl | Q96GR2 | RUO | |
Abbexa | ACSBG2 | abx211443 | Acyl-CoA Synthetase Bubblegum Family Member 2 (ACSBG2) Antibody | Human | Polyclonal | Rabbit | Acyl-CoA Synthetase Bubblegum Family Member 2 (ACSBG2) | Unconjugated | ELISA, IHC | 250 | 50 µl | Q5FVE4 | RUO | |
Abbexa | ACSBG2 | abx211444 | Acyl-CoA Synthetase Bubblegum Family Member 2 (ACSBG2) Antibody | Human | Polyclonal | Rabbit | Acyl-CoA Synthetase Bubblegum Family Member 2 (ACSBG2) | Unconjugated | ELISA, IHC | 250 | 50 µl | Q5FVE4 | RUO | |
Abbexa | ACSBG2 | abx302783 | Acyl-CoA Synthetase Bubblegum Family Member 2 (ACSBG2) Antibody | Human | Polyclonal | Rabbit | Acyl-CoA Synthetase Bubblegum Family Member 2 (ACSBG2) | Unconjugated | ELISA, WB, IHC | 162.5 | 20 µg | Q5FVE4 | RUO | |
Abbexa | ACSBG2 | abx038035 | Acyl-CoA Synthetase Bubblegum Family Member 2 (ACSBG2) Antibody | Human | Polyclonal | Rabbit | Acyl-CoA Synthetase Bubblegum Family Member 2 (ACSBG2) | Unconjugated | ELISA, WB, IHC | 337.5 | 100 µg | RUO |
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