Acyl-CoA Dehydrogenase, Short/Branched Chain (ACADSB) Antibody

Este producto es parte de ACADSB - Acyl-CoA Dehydrogenase, Short/Branched Chain
Acyl-CoA Dehydrogenase, Short/Branched Chain (ACADSB) Antibody
377€ (100 µg)

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Name
Acyl-CoA Dehydrogenase, Short/Branched Chain (ACADSB) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx230067
Tested Applications
ELISA, WB, IHC

Description

ACADSB Antibody is a Rabbit Polyclonal against ACADSB.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
Target: Acyl-CoA Dehydrogenase, Short/Branched Chain (ACADSB)
Immunogen: acyl-Coenzyme A dehydrogenase, short/branched chain
Host
Rabbit
Reactivity
Human, Mouse, Rat
Assay Type
Concentration: 2 mg/ml
Recommended Dilution
WB: 1/200 - 1/2000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
Observed MW: 47 kDa
Purity
≥ 95% (SDS-PAGE)
Purification
Purified by immunogen affinity chromatography.
Size 1
100 µg
Form
Liquid
Tested Applications
ELISA, WB, IHC
Buffer
PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Availability
Shipped within 5-12 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P45954
Gene ID
36
OMIM
600301
Alias
2-MEBCAD,ACAD7,SBCAD
Background
Antibody anti-ACADSB
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Background

The ACADSB gene encodes the enzyme short/branched chain specific acyl-CoA dehydrogenase (SBCAD), which belongs to the acyl-CoA dehydrogenase family. This enzyme is involved in catalyzing the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branched-chain amino acids. ACADSB deficiency can lead to short/branched-chain acyl-CoA dehydrogenase deficiency. The enzyme exhibits substrate specificity towards short branched-chain acyl-CoA derivatives, particularly (S)-2-methylbutyryl-CoA, although it also reacts with other 2-methyl branched chain substrates and short straight chain acyl-CoAs. The encoded protein is initially produced as a mitochondrial precursor, which undergoes cleavage upon import into the mitochondria, resulting in a mature peptide of approximately 43.7 kDa.

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