ACTL6A Cell ELISA Kit
513.5€ (96 tests)
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Name
ACTL6A Cell ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx595698
Tested Applications
ELISA
Description
ACTL6A Cell ELISA Kit is a cell-based ELISA Kit. Cells to be assayed should be seeded onto a clear flat bottom 96 well plate, using poly-L-lysine for non-adherent cells. Cells should be grown to 75-90% confluence and treated prior to carrying out the ELISA.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Immunogen Target | ACTL6A |
| Reactivity | Human, Mouse, Rat |
| Detection Method | Colorimetric |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Tested Applications | ELISA |
| Availability | Shipped within 1-2 weeks. |
| Storage | Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | O96019 |
| Gene ID | 86 |
| OMIM | 604958 |
| Alias | ACTL6,ARPN-BETA,Arp4,BAF53A |
| Background | Elisa Kits for: ACTL6A |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Background
ACTL6A, also known as BAF53A, is a core component of the SWI/SNF chromatin remodeling complex. It interacts with actin-related proteins and histone modifiers to regulate transcriptional activity and chromatin structure. ACTL6A plays a pivotal role in neural development and stem cell maintenance. Structurally, ACTL6A contains an actin-like ATP-binding domain but does not form filaments like traditional actin. Instead, it stabilizes SWI/SNF complexes, enabling precise control over gene expression during differentiation. Mutations or overexpression of ACTL6A have been linked to cancers, particularly gliomas and squamous cell carcinoma, due to its role in regulating proliferation-related genes.
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