Activin A Receptor Type 1B (ACVR1B) Antibody
286€ (100 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Activin A Receptor Type 1B (ACVR1B) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx102966
Tested Applications
IHC, IF/ICC
Description
Polyclonal Antibody to Activin A Receptor Type I B (ACVR1B).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Activin A Receptor Type 1B (ACVR1B) Immunogen: ACVR1B (Ile207-Val385) |
| Host | Rabbit |
| Reactivity | Mouse |
| Recommended Dilution | WB (Predicted): 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | ACTR-IB,ALK-4,Serine/threonine-protein kinase receptor R2 (SKR2) |
| Background | Antibody anti-ACVR1B |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ACVR1B, also known as ALK4, is a type I receptor primarily activated by activins, inhibins, and Nodal ligands. This receptor phosphorylates SMAD2/3 to propagate downstream signaling, which regulates cellular processes such as differentiation, proliferation, and embryonic patterning. ACVR1B is expressed in many tissues, particularly during early development. Mutations in ACVR1B have been associated with tumorigenesis and reproductive disorders due to its role in cell cycle regulation and tissue homeostasis.
Productos relacionados
Activin A Receptor Type 1B (ACVR1B) Antibody
ACVR1B Antibody is a Rabbit Polyclonal antibody against ACVR1B. This gene encodes an activin A type IB receptor. Activin…
Ver producto
Activin A Receptor Type 1B (ACVR1B) Antibody
This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to…
Ver producto
Activin A Receptor Type 1B (ACVR1B) Antibody
Rabbit Polyclonal against the ACVR1B protein.…
Ver producto