Actin Related Protein T2 (ACTRT2) Antibody

Background

ACTRT2 is another member of the actin-related protein T subfamily. It shares significant homology with ACTRT1 but exhibits tissue-specific expression, particularly in germ cells and neurons. Functionally, ACTRT2 participates in cellular motility and actin cytoskeleton remodeling. Unlike canonical actin, ACTRT2 does not polymerize but instead acts as a regulatory protein influencing actin-based processes such as endocytosis and cellular migration. Its expression is tightly regulated during development, and its dysfunction is associated with impaired cytoskeletal dynamics, potentially leading to developmental abnormalities.