Actin-Related Protein 5 (ACTR5) Antibody
292.5€ (80 µl)
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935106861
info@markelab.com
name
Actin-Related Protein 5 (ACTR5) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx034297
tested applications
ELISA, WB, IHC
Description
ACTR5 may be involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Actin-Related Protein 5 (ACTR5) |
| Host | Rabbit |
| Reactivity | Human, Hamster |
| Recommended Dilution | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9H9F9 |
| Alias | ARP5,FLJ12785,HARP5,ARP5 |
| Background | Antibody anti-ACTR5 |
| Status | RUO |
Descripción
ACTR5, also known as ARP5, is a component of chromatin remodeling complexes, such as INO80. Unlike cytoskeletal actin, ACTR5 does not participate in filament formation but interacts with chromatin to regulate nucleosome positioning and transcription. Structurally, ACTR5 has actin-like ATP-binding domains essential for chromatin remodeling. It plays critical roles in DNA repair, replication, and transcriptional activation. Disruption of ACTR5 impairs genomic stability and has been linked to cancer development due to defective chromatin maintenance.
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