Actin-Related Protein 5 (ACTR5) Antibody
357.5€ (100 µg)
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Name
Actin-Related Protein 5 (ACTR5) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx037570
Tested Applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the ACTR5 protein.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Actin-Related Protein 5 (ACTR5) Immunogen: A peptide corresponding to middle region of human ACTR5 protein. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 68 kDa |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | NM_024855 |
| Alias | ARP5,FLJ12785,HARP5,ARP5 |
| Background | Antibody anti-ACTR5 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ACTR5, also known as ARP5, is a component of chromatin remodeling complexes, such as INO80. Unlike cytoskeletal actin, ACTR5 does not participate in filament formation but interacts with chromatin to regulate nucleosome positioning and transcription. Structurally, ACTR5 has actin-like ATP-binding domains essential for chromatin remodeling. It plays critical roles in DNA repair, replication, and transcriptional activation. Disruption of ACTR5 impairs genomic stability and has been linked to cancer development due to defective chromatin maintenance.
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