Actin-Related Protein 5 (ACTR5) Antibody
357.5€ (100 µg)
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935106861
info@markelab.com
name
Actin-Related Protein 5 (ACTR5) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx037570
tested applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the ACTR5 protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Actin-Related Protein 5 (ACTR5) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | NM_024855 |
| Alias | ARP5,FLJ12785,HARP5,ARP5 |
| Background | Antibody anti-ACTR5 |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
ACTR5, also known as ARP5, is a component of chromatin remodeling complexes, such as INO80. Unlike cytoskeletal actin, ACTR5 does not participate in filament formation but interacts with chromatin to regulate nucleosome positioning and transcription. Structurally, ACTR5 has actin-like ATP-binding domains essential for chromatin remodeling. It plays critical roles in DNA repair, replication, and transcriptional activation. Disruption of ACTR5 impairs genomic stability and has been linked to cancer development due to defective chromatin maintenance.
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