Actin-Like Protein 6B (ACTL6B) Antibody
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935106861
info@markelab.com
Precio
169€ (20 µl)
Antibody anti-ACTL6B
proveedor
Abbexareference
abx321429Tested Applications
ELISA, WB, IHCreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
ACTL6B Antibody is a Rabbit Polyclonal against ACTL6B.
Background
ACTL6B, or BAF53B, is a paralog of ACTL6A and functions primarily in post-mitotic neurons. Like ACTL6A, ACTL6B is part of the SWI/SNF chromatin remodeling complex but is specifically associated with neuronal differentiation and synaptic plasticity. Its structure includes conserved ATP-binding motifs and an actin-like fold, contributing to chromatin interactions. ACTL6B is essential for proper neural circuitry development, as it modulates activity-dependent gene expression. Mutations in ACTL6B have been implicated in neurodevelopmental disorders, including intellectual disabilities and autism spectrum disorders, due to impaired neuronal maturation.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Actin-Like Protein 6B (ACTL6B)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB, IHC
purification
Antigen Affinity Chromatography.
recommended dilution
WB: 1/200 - 1/1000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol.
size 1
20 µl
size 2
50 µl
size 3
100 µl
size 4
200 µl
size 5
1 ml
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
ACTL6B
dry ice
No
availability
Shipped within 5-10 working days.
alias
ACTL6,BAF53B,DEE76,EIEE76,IDDSSAD
uniprot id
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