Actin Like 7B (ACTL7B) Antibody
357.5€ (100 µg)
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Name
Actin Like 7B (ACTL7B) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx038064
Tested Applications
ELISA, WB, IHC
Description
Rabbit Polyclonal against the ACTL7B protein.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Actin Like 7B (ACTL7B) Immunogen: Recombinant fragment corresponding to 38-302 AA of human ACTL7B. |
| Host | Rabbit |
| Reactivity | Human |
| Assay Type | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 45 kDa |
| Purification | Purified by Protein A/G column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | Tact1 |
| Background | Antibody anti-ACTL7B |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ACTL7B is closely related to ACTL7A and is also expressed exclusively in the testis. It is essential for spermatid elongation and nuclear condensation during late spermatogenesis. Structurally, ACTL7B contains conserved actin domains but lacks the polymerization capacity seen in conventional actins. It interacts with chromatin remodeling factors to ensure proper histone-to-protamine transition in spermatids. Loss or mutations in ACTL7B can impair spermatid differentiation, resulting in male infertility. Its specialized function highlights the diversity of actin-like proteins in reproductive biology.
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