Actin Gamma 2, Enteric Smooth Muscle (ACTG2) Antibody
221€ (50 µg)
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Name
Actin Gamma 2, Enteric Smooth Muscle (ACTG2) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx329445
Tested Applications
ELISA, WB, IHC, IF/ICC
Description
ACTG2 Antibody is a Rabbit Polyclonal against ACTG2.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Actin Gamma 2, Enteric Smooth Muscle (ACTG2) Immunogen: Synthesized peptide derived from the N-terminal region of human Actin α3. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1/20000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/300, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P63267 |
| Gene ID | 72 |
| Alias | ACT,ACTA3,ACTE,ACTL3,ACTSG,MMIHS5 |
| Background | Antibody anti-ACTG2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ACTG2 encodes gamma-actin, a highly conserved cytoskeletal protein primarily expressed in smooth muscle cells. It plays a vital role in maintaining the structure and contractility of smooth muscle tissues in organs such as the gastrointestinal tract and bladder. As part of the actin family, ACTG2 contributes to cellular processes like motility, intracellular transport, and mechanical force generation. Mutations in ACTG2 have been associated with disorders such as visceral myopathy, characterized by severe dysfunction of smooth muscle contractility. This protein is essential for the proper functioning of muscle-based physiological activities and demonstrates high evolutionary conservation due to its critical cellular roles.
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