Actin-Binding LIM Protein 1 (ABLIM1) Antibody

Background

ABLIM1 is a cytoskeletal protein that plays a critical role in actin filament organization and cellular structure. It is characterized by the presence of LIM domains, which facilitate protein-protein interactions, and actin-binding domains that enable its association with the cytoskeleton. ABLIM1 is expressed in various tissues, including neurons, where it contributes to the stability and dynamics of the actin cytoskeleton. It plays a key role in processes such as cell shape maintenance, migration, and signal transduction. ABLIM1 also interacts with signaling molecules and transcription factors, influencing pathways involved in neuronal differentiation and synaptic activity. Dysregulation of ABLIM1 expression or function has been associated with cytoskeletal abnormalities and neurological disorders, emphasizing its importance in cellular architecture and neural health.