Acidic Nuclear Phosphoprotein 32 Family Member E (ANP32E) Antibody
260€ (50 µl)
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Name
Acidic Nuclear Phosphoprotein 32 Family Member E (ANP32E) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx242194
Tested Applications
ELISA, WB, IHC
Description
ANP32E Antibody is a Rabbit Polyclonal against ANP32E.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Acidic Nuclear Phosphoprotein 32 Family Member E (ANP32E) Immunogen: Synthetic peptide of human ANP32E. |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1/2000 - 1/5000, WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9BTT0 |
| Gene ID | 81611 |
| Alias | LANP-L,LANPL |
| Background | Antibody anti-ANP32E |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ANP32E is a critical regulator of histone dynamics, particularly in the incorporation and removal of histone variant H2A.Z. Through its role in modulating H2A.Z deposition, ANP32E influences chromatin accessibility, gene transcription, and DNA damage repair. It functions as a histone chaperone, ensuring proper regulation of chromatin structure to maintain genomic stability and support essential cellular processes. ANP32E is essential for cellular differentiation, development, and responses to DNA damage. Dysregulation of ANP32E is associated with cancer, where alterations in histone variant dynamics contribute to abnormal transcriptional programs that drive tumorigenesis. Its role in maintaining chromatin integrity highlights its importance in epigenetic regulation and cellular stress responses.
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