Acidic Nuclear Phosphoprotein 32 Family, Member A (ANP32A) Antibody
286€ (100 µl)
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Name
Acidic Nuclear Phosphoprotein 32 Family, Member A (ANP32A) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx104550
Tested Applications
WB, IHC
Description
Polyclonal Antibody to Acidic Nuclear Phosphoprotein 32 Family, Member A (ANP32A).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Acidic Nuclear Phosphoprotein 32 Family, Member A (ANP32A) Immunogen: ANP32A (Glu2-Asp247) |
| Host | Rabbit |
| Reactivity | Mouse |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC (Predicted): 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | ANP32A,C15orf1,LANP |
| Background | Antibody anti-ANP32A |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ANP32A is a multifunctional nuclear phosphoprotein involved in chromatin remodeling, RNA splicing, and cell cycle regulation. ANP32A interacts with histone acetyltransferases (HATs) and histone deacetylases (HDACs), playing a critical role in regulating gene expression and epigenetic modifications. It is also involved in apoptosis and cellular stress responses, where it mediates pathways controlling cell survival and death. ANP32A is implicated in tumorigenesis, acting as either a tumor suppressor or facilitator depending on cellular context. Additionally, it has roles in influenza viral replication by interacting with viral polymerases, making it a key factor in host-virus interactions. Its diverse regulatory functions highlight its importance in nuclear processes and disease mechanisms.
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