Acetyl-Coenzyme A Synthetase, Cytoplasmic (Acss2) Antibody

Este producto es parte de ACSS - Acyl-CoA Synthetase Short-Chain Family Member
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169€ (20 µg)

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935106861
info@markelab.com
name
Acetyl-Coenzyme A Synthetase, Cytoplasmic (Acss2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx319359
tested applications
ELISA, WB

Description

Acss2 Antibody is a Rabbit Polyclonal against Acss2.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Acetyl-Coenzyme A Synthetase, Cytoplasmic (Acss2)
Host
Rabbit
Reactivity
Mouse, Rat
Recommended Dilution
WB: 1/500 - 1/5000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G.
Size 1
20 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
1 mg
Form
Liquid
Tested Applications
ELISA, WB
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9QXG4
Gene ID
60525
Alias
ACAS2,ACECS,ACS,ACSA
Background
Antibody anti-ACSS2
Status
RUO

Descripción

ACSS2 is a cytosolic and nuclear enzyme that catalyzes the activation of acetate into acetyl-CoA, playing a central role in lipid synthesis, histone acetylation, and energy metabolism. It is highly expressed in the liver, adipose tissue, and brain, where it contributes to diverse metabolic and regulatory processes. In the nucleus, ACSS2 provides acetyl-CoA for histone acetylation, influencing gene expression and cellular responses to environmental changes. In the cytoplasm, it supports lipogenesis and cholesterol synthesis by activating acetate for incorporation into fatty acids and sterols. ACSS2 also plays a role in cancer metabolism by providing acetyl-CoA to fuel biosynthetic pathways in rapidly proliferating cells. Dysregulation of ACSS2 has been implicated in cancer progression, metabolic syndromes, and neurodegenerative diseases, highlighting its critical function in integrating metabolic and epigenetic regulation.

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