Abhydrolase Domain Containing 1 (ABHD1) Antibody
377€ (100 µg)
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Name
Abhydrolase Domain Containing 1 (ABHD1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx230044
Tested Applications
ELISA, WB
Description
ABHD1 Antibody is a Rabbit Polyclonal against ABHD1.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Abhydrolase Domain Containing 1 (ABHD1) Immunogen: abhydrolase domain containing 1 |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Assay Type | Concentration: 2 mg/ml |
| Recommended Dilution | WB: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Observed MW: 45 kDa |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96SE0 |
| Gene ID | 84696 |
| OMIM | 612195 |
| Alias | LABH1, Lung alpha/beta hydrolase 1 |
| Background | Antibody anti-ABHD1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ABHD1 is a member of the alpha/beta hydrolase superfamily, functioning as a serine hydrolase with roles in lipid metabolism and signaling. It is expressed in a variety of tissues, including the liver, brain, and immune cells, where it regulates lipid hydrolysis, particularly lysophospholipids, which are critical for maintaining cellular lipid balance. ABHD1 contributes to processes such as lipid signaling, membrane remodeling, and energy metabolism. Emerging studies suggest its involvement in modulating inflammatory responses, likely through its regulation of bioactive lipids that serve as signaling molecules. While the physiological substrates of ABHD1 are not fully characterized, its enzymatic activity has been implicated in maintaining metabolic homeostasis, with dysregulation linked to inflammation and metabolic disorders. The functional versatility of ABHD1 and its potential role in lipid-related diseases make it a promising target for therapeutic exploration.
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