A-Kinase Anchor Protein 8 Like (AKAP8L) Antibody

Este producto es parte de AKAP - A kinase anchor protein
A-Kinase Anchor Protein 8 Like (AKAP8L) Antibody

Pida mas información

935106861

info@markelab.com

Precio

250€ (50 µl)

Antibody anti-AKAP8L

proveedor

Abbexa

reference

abx213051

Tested Applications

ELISA, WB, IHC

reactivity

Human, Mouse

status

RUO

clonality

Polyclonal

Descripción

AKAP8L Antibody is a Rabbit Polyclonal against AKAP8L.


Background

A Kinase Anchor Protein 8-Like (AKAP8L) is a member of the AKAP family of scaffolding proteins that anchor protein kinase A (PKA) and other signaling molecules to specific subcellular locations, thereby compartmentalizing signaling pathways. AKAP8L is predominantly localized in the nucleus, where it plays a critical role in RNA processing, chromatin remodeling, and transcriptional regulation. It is involved in coordinating events such as mRNA splicing and nuclear export, and it may also contribute to mitotic progression through its interactions with chromatin-associated proteins. AKAP8L facilitates the integration of signaling cascades with gene expression, highlighting its role in cellular adaptation to external and internal cues. Dysregulation of AKAP8L has been implicated in cancer and other diseases, where disrupted nuclear signaling and chromatin dynamics affect cell proliferation and survival. Emerging research suggests AKAP8L’s involvement in stress responses, particularly in modulating nuclear processes under conditions of DNA damage or oxidative stress, making it a potential target for therapeutic intervention.

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human, Mouse


immunogen target

A-Kinase Anchor Protein 8 Like (AKAP8L)


host

Rabbit


conjugation

Unconjugated


form

Liquid


tested applications

ELISA, WB, IHC


purification

Antigen Affinity Chromatography.


buffer

PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol.


size 1

50 µl


size 2

100 µl


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

AKAP8L


dry ice

No


availability

Shipped within 5-10 working days.


alias

NAKAP, NAKAP95


note

This product is for research use only.


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