A-Kinase Anchor Protein 5 (AKAP5) Antibody

Descripción

AKAP5 Antibody is a Rabbit Polyclonal antibody against AKAP5. The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT.

Características del producto

clonality

Polyclonal

reactivity

Human, Mouse, Rat

immunogen target

A-Kinase Anchor Protein 5 (AKAP5)

host

Rabbit

conjugation

Unconjugated

form

Liquid

tested applications

WB, IHC

purification

Purified by affinity chromatography.

buffer

PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.

size 1

20 µl

size 2

50 µl

size 3

100 µl

size 4

200 µl

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

AKAP5

dry ice

availability

Shipped within 5-10 working days.

alias

AKAP5, AKAP79

uniprot id

https://www.uniprot.org/uniprotkb/P24588

gene id

https://www.ncbi.nlm.nih.gov/gene/9495

NCBI accession

NP_004848.3

note

This product is for research use only.

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