A Disintegrin And Metalloproteinase With Thrombospondin 7 (ADAMTS7) Antibody
845€ (1 ml)
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935106861
info@markelab.com
name
A Disintegrin And Metalloproteinase With Thrombospondin 7 (ADAMTS7) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx171042
tested applications
WB, IHC, IF/ICC
Description
This product is currently in development. The lead time for this product may be several months. Please contact us at
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | A Disintegrin And Metalloproteinase With Thrombospondin 7 (ADAMTS7) |
| Host | Mouse |
| Reactivity | Rat |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Size 1 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Please enquire. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | COMPase, Type 1 Motif 7,A Disintegrin And Metalloproteinase With Thrombospondin Motifs 7,ADAMTS-7,ADAM-TS 7 |
| Background | Antibody anti-ADAMTS7 |
| Status | RUO |
Descripción
ADAMTS7 (A Disintegrin And Metalloproteinase with Thrombospondin Motifs 7) is another member of the ADAMTS family of proteases. Like other ADAMTS proteins, ADAMTS7 contains multiple domains, including a metalloproteinase domain, a disintegrin-like domain, and thrombospondin type-1 (TSP-1) motifs. ADAMTS7 is expressed in various tissues, including skeletal muscle, heart, brain, and cartilage. Its expression pattern suggests roles in tissue development, maintenance, and homeostasis. ADAMTS7 is implicated in various physiological processes, particularly in extracellular matrix (ECM) remodeling. It plays a role in the turnover and organization of ECM components, including proteoglycans and collagens. Additionally, ADAMTS7 has been linked to angiogenesis, inflammation, and wound healing.Dysregulation of ADAMTS7 has been associated with several diseases and conditions. In particular, ADAMTS7 has been implicated in osteoarthritis, where it may contribute to cartilage degradation and joint inflammation. Studies have also linked ADAMTS7 to atherosclerosis, where it may play a role in plaque formation and vascular remodeling.
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