1-Acylglycerol-3-Phosphate O-Acyltransferase 4 (AGPAT4) Antibody
52€ (10 µg)
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Name
1-Acylglycerol-3-Phosphate O-Acyltransferase 4 (AGPAT4) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx249447
Tested Applications
WB
Description
AGPAT4 Antibody is a Rabbit Polyclonal against AGPAT4.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: 1-Acylglycerol-3-Phosphate O-Acyltransferase 4 (AGPAT4) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9NRZ5 |
| Alias | 1-AGPAT4,LPAAT-delta |
| Background | Antibody anti-AGPAT4 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
AGPAT4 is an enzyme involved in the biosynthesis of phosphatidic acid (PA) by acylating lysophosphatidic acid (LPA) at the sn-2 position. It is localized to the endoplasmic reticulum (ER) and participates in the production of key phospholipids and triglycerides necessary for membrane synthesis and lipid signaling. AGPAT4 is expressed in multiple tissues, with high levels in the brain, suggesting a role in neural lipid metabolism. It is also implicated in lipid remodeling, which affects membrane fluidity and vesicular trafficking. Dysregulation of AGPAT4 has been linked to altered lipid homeostasis and metabolic disorders, though its specific physiological and pathological roles require further study.
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