1-Acylglycerol-3-Phosphate O-Acyltransferase 4 (AGPAT4) Antibody
260€ (50 µl)
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935106861
info@markelab.com
name
1-Acylglycerol-3-Phosphate O-Acyltransferase 4 (AGPAT4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx241181
tested applications
ELISA, IHC
Description
AGPAT4 Antibody is a Rabbit Polyclonal against AGPAT4.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | 1-Acylglycerol-3-Phosphate O-Acyltransferase 4 (AGPAT4) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1/2000 - 1/5000, IHC: 1/25 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9NRZ5 |
| Gene ID | 56895 |
| Alias | 1-AGPAT4,LPAAT-delta |
| Background | Antibody anti-AGPAT4 |
| Status | RUO |
Descripción
AGPAT4 is an enzyme involved in the biosynthesis of phosphatidic acid (PA) by acylating lysophosphatidic acid (LPA) at the sn-2 position. It is localized to the endoplasmic reticulum (ER) and participates in the production of key phospholipids and triglycerides necessary for membrane synthesis and lipid signaling. AGPAT4 is expressed in multiple tissues, with high levels in the brain, suggesting a role in neural lipid metabolism. It is also implicated in lipid remodeling, which affects membrane fluidity and vesicular trafficking. Dysregulation of AGPAT4 has been linked to altered lipid homeostasis and metabolic disorders, though its specific physiological and pathological roles require further study.
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