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Activation-Induced Cytidine Deaminase (AID) is a crucial enzyme involved in the processes of somatic hypermutation (SHM) and class switch recombination (CSR) in B cells, which are fundamental mechanisms for generating antibody diversity in the immune system. Somatic Hypermutation (SHM): AID introduces point mutations in the variable regions of immunoglobulin genes during B cell activation. This process enhances the diversity of antibodies, allowing for the generation of high-affinity antibodies against specific antigens. Class Switch Recombination (CSR): AID mediates the exchange of constant regions (C regions) of immunoglobulin heavy chain genes, resulting in the production of antibodies with different effector functions (e.g., IgM to IgG, IgA, or IgE). This process is essential for optimizing the immune response to different types of pathogens. Despite its critical role in antibody diversification, AID activity can also lead to genomic instability and the development of B cell lymphomas if not tightly regulated. Thus, AID regulation is an area of active research in immunology and cancer biology.
Activation-Induced Cytidine Deaminase (AID) is a pivotal enzyme in the adaptive immune system, essential for the diversification of antibodies through somatic hypermutation and class switch recombination. Its precise regulation and function are critical for effective immune responses, while its dysregulation can lead to immunodeficiency, autoimmunity, and cancer. Understanding AID's role and mechanisms continues to be a significant area of research in immunology and oncology.
Activation Induced Cytidine Deaminase (AICDA)
AID,ARP2,CDA2,HIGM2
En la tabla siguiente se muestra una comparativa de todos los reactivos disponibles en nuestro catálogo (Proteins and Peptides, ELISA Kits, Primary Antibodies) relacionados con AICDA - Activation Induced Cytidine Deaminase
Se muestran ordenados por categorías para poder comparar cómodamente sus características principales. Esta tabla, que contiene un enlace con la ficha de cada producto, es exportable a Excel.
Esta página contiene 16 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
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Abbexa | AICDA | abx555757 | Cow Activation-Induced Cytidine Deaminase (AICDA) ELISA Kit | Cow | Tissue homogenates,Cell lysates,Other biological fluids | 0.156 ng/ml - 10 ng/ml | 687.5 | 96 tests | Q2PT36 | RUO | ||
Abbexa | AICDA | abx555330 | Dog Activation-Induced Cytidine Deaminase (AICDA) ELISA Kit | Dog | Tissue homogenates,Cell lysates,Other biological fluids | 78 pg/ml - 5000 pg/ml | 687.5 | 96 tests | Q75W64 | RUO | ||
Abbexa | AICDA | abx385670 | Human Activation Induced Cytidine Deaminase (AICDA) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.13 ng/ml | 687.5 | 96 tests | Q9GZX7 | RUO |
Abbexa | AICDA | abx556066 | Mouse Activation-Induced Cytidine Deaminase (AICDA) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 31.2 pg/ml - 2000 pg/ml | 687.5 | 96 tests | Q9WVE0 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
FineTest | AICDA | FNab10181 | anti- AICDA antibody | human | polyclonal | Rabbit | Single-stranded DNA cytosine deaminase | IgG | Unconjugated | ELISA, IHC | 100µg | Q9GZX7 | RUO | |
Abbexa | AICDA | abx312572 | Activation-Induced Cytidine Deaminase (AICDA) Antibody (HRP) | Human | Polyclonal | Rabbit | Activation-Induced Cytidine Deaminase (AICDA) | HRP | ELISA | 162.5 | 20 µg | Q9GZX7 | RUO | |
Abbexa | AICDA | abx137308 | Activation-Induced Cytidine Deaminase (AICDA) Antibody | Human | Monoclonal | Mouse | Activation-Induced Cytidine Deaminase (AICDA) | Unconjugated | 225 | 5 µg | RUO | |||
Abbexa | AICDA | abx312573 | Activation-Induced Cytidine Deaminase (AICDA) Antibody (FITC) | Human | Polyclonal | Rabbit | Activation-Induced Cytidine Deaminase (AICDA) | FITC | 162.5 | 20 µg | Q9GZX7 | RUO | ||
Abbexa | AICDA | abx312574 | Activation-Induced Cytidine Deaminase (AICDA) Antibody (Biotin) | Human | Polyclonal | Rabbit | Activation-Induced Cytidine Deaminase (AICDA) | Biotin | ELISA | 162.5 | 20 µg | Q9GZX7 | RUO | |
Abbexa | AICDA | abx212724 | Activation-Induced Cytidine Deaminase (AICDA) Antibody | Human | Polyclonal | Rabbit | Activation-Induced Cytidine Deaminase (AICDA) | Unconjugated | ELISA, IHC | 250 | 50 µl | Q9GZX7 | RUO | |
Abbexa | AICDA | abx318692 | Activation-Induced Cytidine Deaminase (AICDA) Antibody | Human | Polyclonal | Rabbit | Activation-Induced Cytidine Deaminase (AICDA) | Unconjugated | ELISA, WB | 162.5 | 20 µg | Q9GZX7 | RUO | |
Abbexa | AICDA | abx037751 | Activation-Induced Cytidine Deaminase (AICDA) Antibody | Human | Polyclonal | Rabbit | Activation-Induced Cytidine Deaminase (AICDA) | Unconjugated | ELISA, WB, IHC | 337.5 | 100 µg | RUO | ||
Abbexa | AICDA | abx148079 | Activation-Induced Cytidine Deaminase (AICDA) Antibody | Human | Polyclonal | Rabbit | Activation-Induced Cytidine Deaminase (AICDA) | Unconjugated | ELISA, IHC | 350 | 100 µg | Q9GZX7 | RUO | |
Abbexa | AICDA | abx110788 | Activation-Induced Cytidine Deaminase (AICDA) Antibody | Human | Polyclonal | Rabbit | Activation-Induced Cytidine Deaminase (AICDA) | Unconjugated | ELISA, WB | 612.5 | 100 µl | Q9GZX7 | RUO | |
Abbexa | AICDA | abx327184 | Activation-Induced Cytidine Deaminase (AICDA) Antibody | Human | Polyclonal | Rabbit | Activation-Induced Cytidine Deaminase (AICDA) | Unconjugated | ELISA, WB | 187.5 | 50 µg | Q9GZX7 | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | AICDA | abx073366 | Human Activation-Induced Cytidine Deaminase (AICDA) Protein | Human | Recombinant | E. coli | SDS-PAGE | 225 | 5 µg | Q9GZX7 | RUO |
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