Zinc finger MIZ domain-containing protein 1 (ZMIZ1) Antibody (FITC)

Este producto es parte de ZMIZ - Zinc Finger MIZ-Type Containing
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169€ (20 µg)

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935106861
info@markelab.com
name
Zinc finger MIZ domain-containing protein 1 (ZMIZ1) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx349527

Description

Zinc finger MIZ domain-containing protein 1 (ZMIZ1) Antibody (FITC) is a Rabbit Polyclonal antibody conjugated to FITC for the detection of Human ZMIZ1.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Zinc finger MIZ domain-containing protein 1 (ZMIZ1)
Host
Rabbit
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
FITC
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G chromatography.
Size 1
20 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
1 mg
Form
Liquid
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9ULJ6
Alias
MIZ,NEDDFSA,RAI17,TRAFIP10,ZIMP10,PIAS-like protein Zimp10,Retinoic acid-induced protein 17
Background
Antibody anti-ZMIZ1
Status
RUO

Descripción

Zinc Finger MIZ-Type Containing 1 (ZMIZ1) is a transcriptional co-activator and a member of the PIAS-like (protein inhibitor of activated STAT) family which regulates transcription by interacting with transcription factors and chromatin-modifying proteins ZMIZ1 contains a MIZ domain that mediates protein-protein interactions and is involved in enhancing the activity of androgen receptors (AR) SMAD proteins and p53 signaling pathways It contributes to cell proliferation and differentiation particularly in immune cells and hematopoietic stem cells Aberrant expression or mutations in ZMIZ1 have been associated with cancers such as leukemia and breast cancer due to its role in activating oncogenic pathways ZMIZ1 is also implicated in autoimmune diseases such as systemic lupus erythematosus and multiple sclerosis where it influences T-cell activation and immune tolerance highlighting its role in transcriptional regulation and immune homeostasis
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