Zinc Finger And BTB Domain-Containing Protein 38 (ZBTB38) Antibody

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Description
ZBTB38 Antibody is a Rabbit Polyclonal against ZBTB38.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | Zinc Finger And BTB Domain-Containing Protein 38 (ZBTB38) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | WB: 1/500 - 1/5000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purity | ≥ 95% (SDS-PAGE) |
Purification | Purified by immunogen affinity chromatography. |
Size 1 | 100 µg |
Form | Liquid |
Tested Applications | ELISA, WB, IHC |
Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
Availability | Shipped within 5-12 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q8NAP3 |
Gene ID | 253461 |
OMIM | 612218 |
Background | Antibody anti-ZBTB38 |
Status | RUO |
Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
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Transcriptional regulator with bimodal DNA-binding specificity. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to E-box elements(5'-CACGTG-3'). Can also bind specifically to a single methyl-CpG pair. Represses transcription in a methyl-CpG-dependent manner(PubMed:16354688). Plays an important role in regulating DNA replication and common fragile sites(CFS) stability in a RBBP6-and MCM10-dependent manner; represses expression of MCM10 which plays an important role in DNA-replication(PubMed:24726359). Acts as a transcriptional activator. May be involved in the differentiation and/or survival of late postmitotic neurons(By similarity).
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Zinc Finger And BTB Domain-Containing Protein 38 (ZBTB38) Antibody
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