Xeroderma Pigmentosum, Complementation Group C (XPC) Antibody
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Description
XPC Antibody is a Rabbit Polyclonal Antibody against XPC.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Xeroderma Pigmentosum, Complementation Group C (XPC) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | IHC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q01831 |
| Gene ID | 7508 |
| NCBI Accession | NP_004619.3 |
| Background | Antibody anti-XPC |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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Xeroderma Pigmentosum, Complementation Group C (XPC) Antibody
XPC Antibody is a Rabbit Polyclonal Antibody against XPC.
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Xeroderma Pigmentosum, Complementation Group C (XPC) Antibody
This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.
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