X-Ray Repair Cross Complementing 5 (XRCC5) Antibody
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935106861
info@markelab.com
Precio
195€ (20 µl)
Antibody anti-XRCC5
proveedor
Abbexareference
abx004499Tested Applications
ELISA, WB, IHC, IF/ICC, IPreactivity
Human, Mouse, Ratstatus
RUOclonality
PolyclonalDescripción
XRCC5 Antibody is a Rabbit Polyclonal antibody against XRCC5. The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human, Mouse, Rat
immunogen target
X-Ray Repair Cross Complementing 5 (XRCC5)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB, IHC, IF/ICC, IP
purification
Purified by affinity chromatography.
recommended dilution
ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IHC-P: 1/100 - 1/200, IF/ICC: 1/20 - 1/100, IP: 0.5 µg - 4 µg antibody per 200 µg - 400 µg extracts of whole cells. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
size 1
20 µl
size 2
100 µl
size 3
2 × 100 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
XRCC5
dry ice
No
availability
Shipped within 5-10 working days.
uniprot id
NCBI accession
NP_066964.1
note
Concentration: > 0.2 mg/ml -
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Abbexareference
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