Wee1-Like Protein Kinase 2 (WEE2) Antibody

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Description
Wee1 Homolog 2 (S. Pombe) Polyclonal Antibody is a Rabbit Polyclonal antibody against Wee1 Homolog 2 (S. Pombe) Polyclonal Antibody.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Wee1-Like Protein Kinase 2 (WEE2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | 0.1M NaHCO3,0.1M Glycine, 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P0C1S8 |
| Gene ID | 494551 |
| OMIM | 614084 |
| Background | Antibody anti-WEE2 |
| Status | RUO |
Descripción
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WEE2 antibody
Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle(GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation(By similarity).
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