WDFY1 Antibody (Biotin)
169€ (20 µg)
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name
WDFY1 Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx315465
tested applications
ELISA
Description
WDFY1 Antibody (Biotin) is a Rabbit Polyclonal against WDFY1 conjugated to Biotin.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | WDFY1 |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8IWB7 |
| Gene ID | 57590 |
| Alias | WDF1,FENS1,FENS-1,ZFYVE17,Phosphoinositide-binding protein 1,FYVE domain-containing protein localized to endosomes 1,Zinc finger FYVE domain-containing protein 17 |
| Background | Antibody anti-WDFY1 |
| Status | RUO |
Descripción
WD repeat and FYVE domain containing 1 (WDFY1) is a protein that plays an important role in intracellular signaling, particularly in processes related to endocytosis and vesicular trafficking. WDFY1 contains a combination of WD repeats and a FYVE domain, both of which are structural motifs involved in protein-protein interactions. The WD repeat region is known to mediate the formation of multi-protein complexes, while the FYVE domain is responsible for binding phosphoinositides, key lipids in cellular membranes. This protein is involved in the regulation of endosomal trafficking, which is essential for maintaining the proper sorting and recycling of receptors and other cell surface proteins. WDFY1's interaction with the phosphoinositide-binding protein complex allows it to participate in the sorting of endocytic cargo, influencing receptor downregulation and recycling pathways. Given its role in vesicular transport, WDFY1 has been implicated in several cellular processes, including autophagy and immune cell function. Dysfunction of WDFY1 can lead to disruptions in membrane trafficking and autophagy, which have been linked to neurological disorders and immune diseases. Further research into WDFY1's function is necessary to understand its broader role in cellular physiology and disease.
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