WD Repeat And FYVE Domain-Containing Protein 1 (WDFY1) Antibody

Este producto es parte de WDFY - WD repeat and FYVE domain containing
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357.5€ (100 µg)

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935106861
info@markelab.com
name
WD Repeat And FYVE Domain-Containing Protein 1 (WDFY1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx122281
tested applications
ELISA, WB

Description

Rabbit Polyclonal against the WDFY1 protein.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
WD Repeat And FYVE Domain-Containing Protein 1 (WDFY1)
Host
Rabbit
Reactivity
Human
Recommended Dilution
ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified by antigen affinity column chromatography.
Size 1
100 µg
Size 2
1 mg
Form
Lyophilized
Tested Applications
ELISA, WB
Buffer
Prior to lyophilization: 1% BSA and 0.02% NaN3.
Availability
Shipped within 7-15 working days.
Storage
Store at -20 °C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
NCBI Accession
BC040525
Alias
WDF1,FENS1,FENS-1,ZFYVE17,Phosphoinositide-binding protein 1,FYVE domain-containing protein localized to endosomes 1,Zinc finger FYVE domain-containing protein 17
Background
Antibody anti-WDFY1
Status
RUO
Note
Concentration: Lyophilized form: Not applicable.  After reconstitution: 1 mg/ml. -

Descripción

WD repeat and FYVE domain containing 1 (WDFY1) is a protein that plays an important role in intracellular signaling, particularly in processes related to endocytosis and vesicular trafficking. WDFY1 contains a combination of WD repeats and a FYVE domain, both of which are structural motifs involved in protein-protein interactions. The WD repeat region is known to mediate the formation of multi-protein complexes, while the FYVE domain is responsible for binding phosphoinositides, key lipids in cellular membranes. This protein is involved in the regulation of endosomal trafficking, which is essential for maintaining the proper sorting and recycling of receptors and other cell surface proteins. WDFY1's interaction with the phosphoinositide-binding protein complex allows it to participate in the sorting of endocytic cargo, influencing receptor downregulation and recycling pathways. Given its role in vesicular transport, WDFY1 has been implicated in several cellular processes, including autophagy and immune cell function. Dysfunction of WDFY1 can lead to disruptions in membrane trafficking and autophagy, which have been linked to neurological disorders and immune diseases. Further research into WDFY1's function is necessary to understand its broader role in cellular physiology and disease.
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