Vascular Endothelial Growth Factor A (VEGFA) Peptide

Este producto es parte de VEGFA - Vascular Endothelial Growth Factor A
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195€ (100 µg)

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935106861
info@markelab.com
name
Vascular Endothelial Growth Factor A (VEGFA) Peptide
category
Proteins and Peptides
provider
Abbexa
reference
abx616910
tested applications
P-ELISA

Description

Vascular Endothelial Growth Factor A (VEGFA) Peptide is a synthetic peptide. This peptide is used in the production of

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Vascular Endothelial Growth Factor A (VEGFA)
Host
Synthetic
Assay Type
Activity: Not tested.
Sequence Fragment: Internal region, 288-299 AA: C-RIKPHQGQHIGE
Recommended Dilution
BL (predicted): 0.5 mg/ml. Optimal dilutions/concentrations should be determined by the end user.
Conjugation
Unconjugated
Size 1
100 µg
Form
Lyophilized
Tested Applications
P-ELISA
Buffer
Prior to lyophilization: Deionized water.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Gene ID
7422
NCBI Accession
NP_001020537.2, NP_003367.4, NP_001020538.2, NP_001020539.2, etc.
Alias
L-VEGF,MVCD1,VEGF,VPF,Vascular permeability factor
Background
Protein VEGFA
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Reconstitute in deionized water.

Descripción

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VEGFA, also named as VEGF or VPF, belongs to the PDGF/VEGF growth factor family. It is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. VEGFA induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. Defects in VEGFA are a cause of susceptibility to microvascular complications of diabetes type 1(MVCD1). VEGFA has 13 isoforms with MW 16kd to 45kd. Some isoforms has homodimer form, such as VEGFA189(38kd), VEFGA110(34kd). VEGFA is a 34kd to 42kd, dimeric, disulfide-bound glycoprotein. VEGF-A exists in at least seven homodimeric isoforms. The monomers consist of 121, 145, 148, 165, 183, 189, or 206 amino acids(PMID:15602010).

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