Vascular Cell Adhesion Molecule 1 (VCAM1) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Rabbit Polyclonal against the Vascular Cell Adhesion Molecule 1 / CD106 (VCAM1) protein.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Vascular Cell Adhesion Molecule 1 (VCAM1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | V-CAM 1,VCAM-1,INCAM-100,CD106 |
| Background | Antibody anti-VCAM1 |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
VCAM1 is a transmembrane glycoprotein and member of the immunoglobulin superfamily that plays a key role in cell adhesion, particularly in leukocyte-endothelial interactions during inflammation VCAM1 is expressed on endothelial cells in response to pro-inflammatory cytokines such as TNF-α and IL-1β where it mediates the adhesion and transmigration of leukocytes, including monocytes and lymphocytes, into inflamed tissues VCAM1 interacts with its ligand VLA-4 (integrin α4β1) to facilitate immune cell recruitment during acute and chronic inflammatory responses VCAM1 is implicated in various diseases including atherosclerosis, where it promotes monocyte adhesion to endothelial cells and contributes to plaque formation Elevated VCAM1 levels are also associated with rheumatoid arthritis, multiple sclerosis, and other autoimmune disorders, where persistent inflammation leads to tissue damage VCAM1 serves as a biomarker for endothelial activation and vascular inflammation, making it a potential target for therapeutic interventions aimed at reducing leukocyte recruitment and chronic inflammation
Related Products
Human Vascular Cell Adhesion Molecule 1 (VCAM1) ELISA Kit
Human Vascular Cell Adhesion Molecule 1 / CD106 (VCAM1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Vascular Cell Adhesion Molecule 1 / CD106 (VCAM1) concentrations in tissue homogenates, cell lysates and other biological fluids.
Ver Producto
Rat Vascular Cell Adhesion Molecule 1 (VCAM1) ELISA Kit
Rat Vascular Cell Adhesion Molecule 1 / CD106 (VCAM1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Rat Vascular Cell Adhesion Molecule 1 / CD106 (VCAM1) concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.
Ver Producto
Dog Vascular Cell Adhesion Molecule 1 (VCAM1) CLIA Kit
Dog Vascular Cell Adhesion Molecule 1 / CD106 (VCAM1) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma, tissue homogenates and other biological fluids.
Ver Producto