Vascular Cell Adhesion Molecule 1 (VCAM1) Antibody
Pida mas información
935106861
info@markelab.com
Precio
212.5€ (0.1 mg)
Antibody anti-VCAM1
proveedor
Abbexareference
abx140597Tested Applications
IHC-F, FCM, IP, FUNCreactivity
Mousestatus
RUOclonality
MonoclonalDescripción
Vascular Cell Adhesion Protein 1 (VCAM1) Antibody is a Rat Monoclonal Antibody against Vascular Cell Adhesion Protein 1 (VCAM1).
Background
VCAM1 is a transmembrane glycoprotein and member of the immunoglobulin superfamily that plays a key role in cell adhesion, particularly in leukocyte-endothelial interactions during inflammation VCAM1 is expressed on endothelial cells in response to pro-inflammatory cytokines such as TNF-α and IL-1β where it mediates the adhesion and transmigration of leukocytes, including monocytes and lymphocytes, into inflamed tissues VCAM1 interacts with its ligand VLA-4 (integrin α4β1) to facilitate immune cell recruitment during acute and chronic inflammatory responses VCAM1 is implicated in various diseases including atherosclerosis, where it promotes monocyte adhesion to endothelial cells and contributes to plaque formation Elevated VCAM1 levels are also associated with rheumatoid arthritis, multiple sclerosis, and other autoimmune disorders, where persistent inflammation leads to tissue damage VCAM1 serves as a biomarker for endothelial activation and vascular inflammation, making it a potential target for therapeutic interventions aimed at reducing leukocyte recruitment and chronic inflammation
Características del producto
category
Primary Antibodies
clonality
Monoclonal
reactivity
Mouse
immunogen target
Vascular Cell Adhesion Molecule 1 (VCAM1)
host
Rat
conjugation
Unconjugated
tested applications
IHC-F, FCM, IP, FUNC
purification
Purified by Protein G affinity chromatography.
buffer
Azide free PBS solution, 0.2 µm filter sterilized.
size 1
0.1 mg
storage
Store at 2-8°C. Do not freeze.
or code
VCAM1
dry ice
No
availability
Shipped within 5-12 working days.
alias
V-CAM 1,VCAM-1,INCAM-100,CD106
uniprot id
note
This product is for research use only.
Quizá le pueda interesar
Human Vascular Cell Adhesion Molecule 1 (VCAM1) ELISA Kit
proveedor
Abbexareference
abx050229Tested Applications
ELISAreactivity
Humanstatus
RUOHuman Vascular Cell Adhesion Molecule 1 / CD106 (VCAM1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurem...
493.75€ (96 tests)
Ver másVascular Cell Adhesion Molecule 1 (VCAM1) Antibody
proveedor
Abbexareference
abx103675Tested Applications
WB, IHC, IF/ICCreactivity
Humanstatus
RUOclonality
PolyclonalPolyclonal Antibody to Vascular Cell Adhesion Molecule 1 / CD106 (VCAM1).
212.5€ (100 µl)
Ver másDog Vascular Cell Adhesion Molecule 1 (VCAM1) ELISA Kit
proveedor
Abbexareference
abx258011Tested Applications
ELISAreactivity
Dogstatus
RUODog Vascular Cell Adhesion Molecule 1 / CD106 (VCAM1) ELISA Kit is an ELISA Kit for the in vitro quantitative measuremen...
687.5€ (96 tests)
Ver más