Vacuolar Protein Sorting-Associated Protein 53 Homolog (VPS53) Antibody
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Description
Rabbit Polyclonal against the VPS53 protein.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Vacuolar Protein Sorting-Associated Protein 53 Homolog (VPS53) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/20000 - 1/80000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by antigen affinity column chromatography. |
| Size 1 | 100 µg |
| Size 2 | 1 mg |
| Form | Lyophilized |
| Tested Applications | ELISA, WB |
| Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
| Availability | Shipped within 7-15 working days. |
| Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Background | Antibody anti-VPS53 |
| Status | RUO |
| Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
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VPS53 antibody
Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network(TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD(PubMed:15878329, PubMed:18367545). Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor(TFRC) to the plasma membrane(PubMed:25799061).
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Vacuolar Protein Sorting-Associated Protein 53 Homolog (VPS53) Antibody
Rabbit Polyclonal against the VPS53 protein.
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