Vacuolar Protein Sorting-Associated Protein 33A (VPS33A) Antibody
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Description
Vacuolar Protein Sorting 33 Homolog A (S. Cerevisiae) Antibody is a Rabbit Polyclonal antibody against Vacuolar Protein Sorting 33 Homolog A (S. Cerevisiae).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Vacuolar Protein Sorting-Associated Protein 33A (VPS33A) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96AX1 |
| Gene ID | 65082 |
| OMIM | 610034 |
| Background | Antibody anti-VPS33A |
| Status | RUO |
Descripción
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VPS33A antibody
Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations(PubMed:23351085, PubMed:24554770, PubMed:25266290, PubMed:25783203). Required for fusion of endosomes and autophagosomes with lysosomes; the function is dependent on its association with VPS16 but not VIPAS39(PubMed:25783203). The function in autophagosome-lysosome fusion implicates STX17 but not UVRAG(PubMed:24554770).
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Vacuolar Protein Sorting-Associated Protein 33A (VPS33A) Antibody
Rabbit Polyclonal against the VPS33A protein.
Ver ProductoVacuolar Protein Sorting-Associated Protein 33A (VPS33A) Antibody
Vacuolar Protein Sorting 33 Homolog A (S. Cerevisiae) Antibody is a Rabbit Polyclonal antibody against Vacuolar Protein Sorting 33 Homolog A (S. Cerevisiae).
Ver Producto