V-Type Proton ATPase Subunit B, Brain Isoform (ATP6V1B2) Antibody
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Description
ATP6V1B2 Antibody is a Rabbit Polyclonal antibody against ATP6V1B2. This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | V-Type Proton ATPase Subunit B, Brain Isoform (ATP6V1B2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P21281 |
| Gene ID | 526 |
| NCBI Accession | NP_001684.2 |
| OMIM | 124480 |
| Background | Antibody anti-ATP6V1B2 |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
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ATP6V1B2 antibody
Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
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V-Type Proton ATPase Subunit B, Brain Isoform (ATP6V1B2) Antibody
ATP6V1B2 Antibody is a Rabbit Polyclonal antibody against ATP6V1B2. This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.
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V-Type Proton ATPase Subunit B, Brain Isoform (ATP6V1B2) Antibody
Rabbit Polyclonal against the ATP6V1B2 protein.
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