UV Radiation Resistance-Associated Gene Protein (UVRAG) Antibody (Biotin)
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Description
UVRAG Antibody (Biotin) is a Rabbit Polyclonal against UVRAG.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | UV Radiation Resistance-Associated Gene Protein (UVRAG) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/1000, IF/ICC: 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Purification | Peptide Affinity Purified |
| Size 1 | 100 µg |
| Tested Applications | WB, IF/ICC |
| Buffer | PBS, 50% glycerol, 0.09% sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9P2Y5 |
| Gene ID | 7405 |
| NCBI Accession | NP_003360.2 |
| Background | Antibody anti-UVRAG |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.
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UV Radiation Resistance-Associated Gene Protein (UVRAG) Antibody
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UVRAG complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI (3) KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer.
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